TIGR Parasites Database

Parasite genomes that are in the process of being sequenced.

* Size estimated from pulsed field gels (see chromosome nomenclature)

** Current funding at NIH may not be sufficient to finish these chromosomes. Submission for renewal of the NIH-funded grant to TIGR will request sufficient to finish the megabase chromosomes, including VII, VIII and any remaining of III and V.
Genome Strain Domain Size (Mb) Sequencing Center Funding Status Status or Anticipated Publication
Trypanosoma brucei TREU 927/4 E 35


Chromosome I a/b 1.15/1.2  Sanger Beowulf almost complete
Chromosome II a/b 1.25/1.3 TIGR NIAID almost complete
Chromosome III a/b 1.62/1.75 TIGR NIAID** not started
Chromosome IV a/b 1.62/1.75 TIGR NIAID in progress
Chromosome V a/b 1.68/1.75 TIGR NIAID** not started
Chromosome VI a/b 1.7/2.0 TIGR NIAID in progress
Chromosome VII a/b 2.1/2.1 TIGR submission to NIAID planned Decision expected late 2000 (not started)
Chromosome VIII a/b 2.1/2.2 TIGR submission to NIAID planned Decision expected late 2000 (not started)
Chromosome IX a/b 3.3/3.5 Sanger submission to Beowulf Decision expected April 2000 (not started)
Chromosome X 4.4/4.4 Sanger submission to Beowulf Decision expected April 2000 (not started)
Chromosome XI 5.2/5.2 Sanger submission to Beowulf Decision expected April 2000 (not started)
Trypanosoma cruzi CL Brener E 40 TIGR NIAID
Entamoeba histolytica EHA-1 E 40 TIGR NIAID
Plasmodium falciparum clone 3D7 E        
Chromosome 1 0.7 Sanger Centre Wellcome Trust
Chromosome 2 0.95 TIGR / NMRC NIAID, DoD Gardner et. al., Science 282:1126-1132 (1998)
Chromosome 3 1.05 Sanger Centre Wellcome Trust Bowman et. al., Nature 400:532-538 (1999)
Chromosomes 4-9 1.3 - 1.6 Sanger Centre Wellcome Trust random sequencing and closure
Chromosome 10 1.75 TIGR / NMRC NIAID, DoD
Chromosome 11 2.1 TIGR / NMRC NIAID, DoD
Chromosome 12 2.4 Stanford University Burroughs Wellcome Fund in closure
Chromosome 13 3.1 Sanger Centre Wellcome Trust in closure
Chromosome 14 3.4 TIGR / NMRC Burroughs Wellcome Fund 1999

Chromosome sizes for P. falciparum were determined by sequencing or optical mapping (Lai, Z., J. Jing, et al. (1999). "A shotgun optical map of the entire Plasmodium falciparum genome." Nature Genetics 23: 309-313).