EGAD was constructed by extraction and curation of sequences from GenBank to create a non-redundant set of human transcript (HT) sequences and non-human transcript (ET) sequences. In some cases, HTs/ETs were created by splicing together distinct GenBank accessions for each exon in those transcripts, or by splicing exons from a genomic sequence.
Each HT sequence is linked to a human gene (HG). An HG may have more than one HT due to alternative splicing. Alternative splice forms of a gene are linked in HG and HT reports.
HG and HT/ET names have been curated for consistent nomenclature. Cellular roles have been assigned to each HT/ET. Tissue distribution information is available for most HTs/ETs.
Extensive expression information, including positions of overlapping Expressed Sequence Tags (ESTs), is available in HT/ET reports, for most HTs/ETs, with links to TIGR's Gene Indices. Clones for HTs/ETs may also be available through the TIGR/ATCC Special Collection.
The curated HT/ET data set is available as a multiple FastA format file, please go to TIGR's data licensing page for more information.
EGAD is accessed through the following queries:
- A name search in which the user supplies a gene product name will return a list of matching HTs/ETs and their identifications.
- Sequence reports can be generated for Human Transcripts (HTs)or non-human transcripts (ET) or Human Genes (HGs).
EGAD has been implemented using the Sybase Database Management Software.
For WWW specific Comments/Questions send mail to www@tigr.org.
For EGAD Comments/Questions send mail to egad@tigr.org.
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