The TIGR Trypanosoma brucei Genome Project

Listed below is a collection of information on Trypanosoma brucei genome research at TIGR. Please follow the links to get more detailed information for each project.

Funding for this project is being provided by the National Institute of Allergy and Infectious Diseases (NIAID), R01AI43062

• Introduction and Sequencing methodology
  A brief summary of the Trypanosoma brucei genome project and a detailed description of our sequencing strategy. Sequences from the ends of BAC clones provide highly specific markers and are used in a map-as-you-go strategy for genome sequencing.
   
• End Sequencing and Gene Discovery
  A database of ~47,000 end sequences generated at TIGR from BAC, P1 and small-insert random sheared libraries can be searched by clone name or sequence.
   
• BAC Sequencing at TIGR
  The progress of our contiguous sequencing project can be viewed here.
   
• Trypanosoma brucei Genome Annotation Database (TGAD)
  This database contains every contiguous sequence derived from the TIGR sequencing project. Annotated sequences are displayed based on their map position and are searchable by BAC clone name as well as by gene name.
   
• Trypanosoma brucei Gene Index (TbGI)
  All publicly available T. brucei ESTs as well as transcripts from Genbank have been assembled into contigs and built into the Trypanosoma brucei Gene Index (TbGI).
   
• Data Release Policy
  Documentation on the Data Release.
   
• A FAQ for this site
  Currently contains information on obtaining BAC, P1 and random sheared DNA clones.
   
• Trypanosoma brucei links
  Links to information on Trypanosoma brucei Genome and tools available from other sites.